What Do Athletes Need to Consider? While creatine is safe and effective with no prevalent side effects, athletes should keep the following in mind: Activity type: Creatine is best suited to short-duration, high-intensity activities like weightlifting and sprinting. Tailored Dose: Larger athletes may need a higher maintenance dose. Hydration: Creatine draws water into muscle cells, which means it may increase the body’s need for water. 6
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